Detalhe da pesquisa
1.
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
Cell
; 171(6): 1437-1452.e17, 2017 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29195078
2.
Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions.
Cell
; 162(5): 1051-65, 2015 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26300125
3.
Landscape of cohesin-mediated chromatin loops in the human genome.
Nature
; 583(7818): 737-743, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728247
4.
Impact of regulatory variation across human iPSCs and differentiated cells.
Genome Res
; 28(1): 122-131, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29208628
5.
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues.
Nat Methods
; 14(10): 959-962, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28846090
6.
Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map.
PLoS Biol
; 15(11): e2003213, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29190685
7.
Discovering epistatic feature interactions from neural network models of regulatory DNA sequences.
Bioinformatics
; 34(17): i629-i637, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30423062
8.
CrowdVariant: a crowdsourcing approach to classify copy number variants.
Pac Symp Biocomput
; 24: 224-235, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30864325
9.
Deciphering regulatory DNA sequences and noncoding genetic variants using neural network models of massively parallel reporter assays.
PLoS One
; 14(6): e0218073, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31206543
10.
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements.
Nat Commun
; 10(1): 4063, 2019 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31492858
11.
Discovery of common and rare genetic risk variants for colorectal cancer.
Nat Genet
; 51(1): 76-87, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30510241
12.
Prediction of protein-ligand interactions from paired protein sequence motifs and ligand substructures.
Pac Symp Biocomput
; 23: 20-31, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29218866
13.
Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin.
Cancer Discov
; 8(10): 1316-1331, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30228179
14.
Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis.
Nat Med
; 23(3): 291-300, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28191885
15.
Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.
Nat Genet
; 49(11): 1602-1612, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28945252
16.
Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data.
PLoS One
; 12(11): e0186518, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29161273
17.
Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution.
Nat Genet
; 48(10): 1193-203, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27526324
18.
An Arntl2-Driven Secretome Enables Lung Adenocarcinoma Metastatic Self-Sufficiency.
Cancer Cell
; 29(5): 697-710, 2016 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27150038